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N4BP1 Antibody

Catalog Number:

34845
other_names: Nedd4 binding protein 1; NEDD4-binding protein 1;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75113
NCBI Gene ID: 9683

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human N4BP1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total N4BP1 protein.

Applications:

WB

Background:

Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates By similarity.

Ishikawa K., DNA Res. 5:169-176(1998).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Matsuoka S., Science 316:1160-1166(2007).

References:

appl_detail:

Western blotting: 1:500~1:3000

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