Product Datasheet
N4BP1 Antibody
Catalog Number: 34845
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O75113
NCBI Gene ID: 9683
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human N4BP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Nedd4 binding protein 1; NEDD4-binding protein 1;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total N4BP1 protein.
- Background:
- Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates By similarity.
Ishikawa K., DNA Res. 5:169-176(1998).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Matsuoka S., Science 316:1160-1166(2007).
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