PTGR1 Antibody

Catalog Number:

34841

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q14914
NCBI Gene ID: 22949

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human PTGR1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PTGR1 protein.

Applications:

WB

Background:

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha By similarity. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

Humphray S.J., Nature 429:369-374(2004).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Yokomizo T., J. Biol. Chem. 271:2844-2850(1996)

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF