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MAZ Antibody

Catalog Number:

34812
other_names: Myc-associated zinc finger protein; MAZI; Purine-binding transcription factor; Pur-1; ZF87

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P56270
NCBI Gene ID: 4150

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MAZ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAZ protein.

Applications:

WB

Background:

May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.

Bossone S.A., Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).
Pyrc J.J., Biochemistry 31:4102-4110(1992).
Tsutsui H., Biochem. Biophys. Res. Commun. 226:801-809(1996).

References:

appl_detail:

Western blotting: 1:500~1:3000

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