Product Datasheet
MAZ Antibody
Catalog Number: 34812
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P56270
NCBI Gene ID: 4150
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MAZ.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Myc-associated zinc finger protein; MAZI; Purine-binding transcription factor; Pur-1; ZF87
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MAZ protein.
- Background:
- May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Bossone S.A., Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).
Pyrc J.J., Biochemistry 31:4102-4110(1992).
Tsutsui H., Biochem. Biophys. Res. Commun. 226:801-809(1996).
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