MINPP1 Antibody

Catalog Number:

34811

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UNW1
NCBI Gene ID: 9562

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MINPP1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MINPP1 protein.

Applications:

WB

Background:

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).

Caffrey J.J., FEBS Lett. 442:99-104(1999).
Chi H., Genomics 56:324-336(1999).
Wiemann S., Genome Res. 11:422-435(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF