Product Datasheet
MINPP1 Antibody
Catalog Number: 34811
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UNW1
NCBI Gene ID: 9562
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MINPP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- EC 3.1.3.62; inositol (1; 3; 4; 5)-tetrakisphosphate 3-phosphatase
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MINPP1 protein.
- Background:
- Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
Caffrey J.J., FEBS Lett. 442:99-104(1999).
Chi H., Genomics 56:324-336(1999).
Wiemann S., Genome Res. 11:422-435(2001).
© Signalway Biotechnology All Rights Reserved.