MBL2 Antibody

Catalog Number:

34776

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11226
NCBI Gene ID: 4153

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MBL2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MBL2 protein.

Applications:

WB

Background:

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988).
Sastry K., J. Exp. Med. 170:1175-1189(1989).
Taylor M.E., Biochem. J. 262:763-771(1989).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF