Product Datasheet  
MBL2 Antibody  
Catalog Number: 34776  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P11226
    NCBI Gene ID: 4153
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human MBL2.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Mannose-binding protein C; MBP-C; MBP1; Mannan-binding protein; Mannose-binding lectin
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total MBL2 protein.
  • Applications：  
  • WB
  • Background：  
  • Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

    Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988).
    Sastry K., J. Exp. Med. 170:1175-1189(1989).
    Taylor M.E., Biochem. J. 262:763-771(1989).




 
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