MASP2 Antibody

Catalog Number:

34775

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O00187
NCBI Gene ID: 10747

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MASP2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MASP2 protein.

Applications:

WB

Background:

Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.

Thiel S., Nature 386:506-510(1997).
Takahashi M., Int. Immunol. 11:859-863(1999).
Stover C.M., J. Immunol. 162:3481-3490(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF