Product Datasheet
MASP2 Antibody
Catalog Number: 34775
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O00187
NCBI Gene ID: 10747
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human MASP2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Mannan-binding lectin serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2; MBL-associated serine protease 2;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total MASP2 protein.
- Background:
- Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Thiel S., Nature 386:506-510(1997).
Takahashi M., Int. Immunol. 11:859-863(1999).
Stover C.M., J. Immunol. 162:3481-3490(1999).
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