SLC27A4 Antibody

Catalog Number:

34761

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q6P1M0
NCBI Gene ID: 10999

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SLC27A4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC27A4 protein.

Applications:

IF

Background:

Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones By similarity.

Fitscher B.A., Biochim. Biophys. Acta 1443:381-385(1998).
Humphray S.J., Nature 429:369-374(2004).
Colinge J., Submitted (OCT-2008) to UniProtKB.

References:

appl_detail:

Immunofluorescence: 1:100~1:500

Datasheet PDF