Product Datasheet
SLC27A4 Antibody
Catalog Number: 34761
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q6P1M0
NCBI Gene ID: 10999
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human SLC27A4.
- appl_detail:
Immunofluorescence: 1:100~1:500
- other_names:
- Long-chain fatty acid transport protein 4; EC 6.2.1.-; Fatty acid transport protein 4; FATP-4; Solute carrier family 27 member 4
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total SLC27A4 protein.
- Background:
- Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones By similarity.
Fitscher B.A., Biochim. Biophys. Acta 1443:381-385(1998).
Humphray S.J., Nature 429:369-374(2004).
Colinge J., Submitted (OCT-2008) to UniProtKB.
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