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LIPI Antibody

Catalog Number:

34760
other_names: EC 3.1.1.-; lipase member I; LPD lipase; LPDL; membrane-associated phosphatidic acid-selective phospholipase A1-beta

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q6XZB0
NCBI Gene ID: 149998

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human LIPI.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LIPI protein.

Applications:

WB

Background:

Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).

Hiramatsu T., J. Biol. Chem. 278:49438-49447(2003).
Wen X.-Y., Hum. Mol. Genet. 12:1131-1143(2003).
Hattori M., Nature 405:311-319(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

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