Product Datasheet
LIPI Antibody
Catalog Number: 34760
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q6XZB0
NCBI Gene ID: 149998
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human LIPI.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- EC 3.1.1.-; lipase member I; LPD lipase; LPDL; membrane-associated phosphatidic acid-selective phospholipase A1-beta
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total LIPI protein.
- Background:
- Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
Hiramatsu T., J. Biol. Chem. 278:49438-49447(2003).
Wen X.-Y., Hum. Mol. Genet. 12:1131-1143(2003).
Hattori M., Nature 405:311-319(2000).
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