LILRB4 Antibody

Catalog Number:

34759

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8NHJ6
NCBI Gene ID: 11006

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human LILRB4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LILRB4 protein.

Applications:

IF

Background:

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Arm J.P., J. Immunol. 159:2342-2349(1997).
Borges L., J. Immunol. 159:5192-5196(1997).
Liu W.R., Immunogenetics 51:659-669(2000).

References:

appl_detail:

Immunofluorescence: 1:100~1:500

Datasheet PDF