Product Datasheet  
LILRB4 Antibody  
Catalog Number: 34759  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q8NHJ6
    NCBI Gene ID: 11006
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human LILRB4.
  • reactivity：  
  • Hu
  • appl_detail：  


  • Immunofluorescence: 1:100~1:500
  • other_names：  
  • Leukocyte immunoglobulin-like receptor subfamily B member 4 ; Leukocyte immunoglobulin-like receptor 5; LIR-5; Immunoglobulin-like transcript 3; ILT-3
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total LILRB4 protein.
  • Applications：  
  • IF
  • Background：  
  • Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

    Arm J.P., J. Immunol. 159:2342-2349(1997).
    Borges L., J. Immunol. 159:5192-5196(1997).
    Liu W.R., Immunogenetics 51:659-669(2000).



 
© Signalway Biotechnology All Rights Reserved.