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HLA-DOB Antibody

Catalog Number:

34736
other_names: HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P13765
NCBI Gene ID: 3112

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human HLA-DOB.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HLA-DOB protein.

Applications:

WB

Background:

Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Tonnelle C., EMBO J. 4:2839-2847(1985).
Jonsson A.-K., Immunogenetics 29:411-413(1989).
Beck S., J. Mol. Biol. 228:433-441(1992).

References:

appl_detail:

Western blotting: 1:500~1:3000

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