Product Datasheet
HLA-DOB Antibody
Catalog Number: 34736
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P13765
NCBI Gene ID: 3112
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from N-terminal of human HLA-DOB.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total HLA-DOB protein.
- Background:
- Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Tonnelle C., EMBO J. 4:2839-2847(1985).
Jonsson A.-K., Immunogenetics 29:411-413(1989).
Beck S., J. Mol. Biol. 228:433-441(1992).
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