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HLA-DOA Antibody

Catalog Number:

34735
other_names: HLA class II histocompatibility antigen; DO alpha chain [Precursor]; MHC class II antigen DOA; MHC DZ alpha; MHC DN-alpha

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P06340
NCBI Gene ID: 3111

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human HLA-DOA.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HLA-DOA protein.

Applications:

WB

Background:

Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.

Trowsdale J., EMBO J. 4:2231-2237(1985).
Jonsson A.-K., Immunogenetics 29:411-413(1989).
Young J.A., Immunogenetics 31:386-388(1990).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF

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