Product Datasheet
HLA-DOA Antibody
Catalog Number: 34735
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P06340
NCBI Gene ID: 3111
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human HLA-DOA.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- HLA class II histocompatibility antigen; DO alpha chain [Precursor]; MHC class II antigen DOA; MHC DZ alpha; MHC DN-alpha
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total HLA-DOA protein.
- Background:
- Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Trowsdale J., EMBO J. 4:2231-2237(1985).
Jonsson A.-K., Immunogenetics 29:411-413(1989).
Young J.A., Immunogenetics 31:386-388(1990).
© Signalway Biotechnology All Rights Reserved.