GDF15 Antibody

Catalog Number:

34712

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q99988
NCBI Gene ID: 9518

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human GDF15.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GDF15 protein.

Applications:

WB

Background:

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]

Hromas R., Biochim. Biophys. Acta 1354:40-44(1997).
Yokoyama-Kobayashi M., J. Biochem. 122:622-626(1997).
Bootcov M.R., Proc. Natl. Acad. Sci. U.S.A. 94:11514-11519(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF