Product Datasheet
GDF15 Antibody
Catalog Number: 34712
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q99988
NCBI Gene ID: 9518
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human GDF15.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- GDF-15; growth differentiation factor 15; MIC-1; MIC1; NAG-1
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GDF15 protein.
- Background:
- Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]
Hromas R., Biochim. Biophys. Acta 1354:40-44(1997).
Yokoyama-Kobayashi M., J. Biochem. 122:622-626(1997).
Bootcov M.R., Proc. Natl. Acad. Sci. U.S.A. 94:11514-11519(1997).
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