ELOVL4 Antibody

Catalog Number:

34672

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9GZR5
NCBI Gene ID: 6785

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ELOVL4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ELOVL4 protein.

Applications:

WB

Background:

Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.

Zhang K., Nat. Genet. 27:89-93(2001).
Edwards A.O., Invest. Ophthalmol. Vis. Sci. 42:2652-2663(2001).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF