Product Datasheet
ELOVL4 Antibody
Catalog Number: 34672
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9GZR5
NCBI Gene ID: 6785
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ELOVL4.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Elongation of very long chain fatty acids protein 4;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ELOVL4 protein.
- Background:
- Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.
Zhang K., Nat. Genet. 27:89-93(2001).
Edwards A.O., Invest. Ophthalmol. Vis. Sci. 42:2652-2663(2001).
Ota T., Nat. Genet. 36:40-45(2004).
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