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EFEMP1 Antibody

Catalog Number:

34665
other_names: EGF-containing fibulin-like extracellular matrix protein 1; Fibulin-3; FIBL-3; Fibrillin-like protein; Extracellular protein S1-5

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q12805
NCBI Gene ID: 2202

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human EFEMP1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EFEMP1 protein.

Applications:

WB

Background:

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Lecka-Czernik B., Mol. Cell. Biol. 15:120-128(1995).
Ikegawa S., Genomics 35:590-592(1996).
Giltay R., Matrix Biol. 18:469-480(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

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