Product Datasheet
EFEMP1 Antibody
Catalog Number: 34665
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q12805
NCBI Gene ID: 2202
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human EFEMP1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- EGF-containing fibulin-like extracellular matrix protein 1; Fibulin-3; FIBL-3; Fibrillin-like protein; Extracellular protein S1-5
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total EFEMP1 protein.
- Background:
- Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Lecka-Czernik B., Mol. Cell. Biol. 15:120-128(1995).
Ikegawa S., Genomics 35:590-592(1996).
Giltay R., Matrix Biol. 18:469-480(1999).
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