DNAJB11 Antibody

Catalog Number:

34657

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UBS4
NCBI Gene ID: 51726

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DNAJB11.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DNAJB11 protein.

Applications:

WB IHC

Background:

Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Ohtsuka K., Cell Stress Chaperones 5:98-112(2000).
Yu M., J. Biol. Chem. 275:24984-24992(2000).
Bies C., Biol. Chem. 385:389-395(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF