Product Datasheet  
DNAJB11 Antibody  
Catalog Number: 34657  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9UBS4
    NCBI Gene ID: 51726
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human DNAJB11.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • ABBP-2; ABBP2; DJB11; DnaJ (Hsp40) homolog; subfamily B
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total DNAJB11 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

    Ohtsuka K., Cell Stress Chaperones 5:98-112(2000).
    Yu M., J. Biol. Chem. 275:24984-24992(2000).
    Bies C., Biol. Chem. 385:389-395(2004).



 
© Signalway Biotechnology All Rights Reserved.