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APPL1 Antibody

Catalog Number:

34641
other_names: Adaptor protein APPL; Adaptor protein containing pH domain; PTB domain and leucine zipper motif; DIP13 alpha; DP13A

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UKG1
NCBI Gene ID: 26060

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human APPL1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total APPL1 protein.

Applications:

WB

Background:

Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.

Chen Y.Q., J. Biol. Chem. 277:26281-26285(2002).
Elledge S.J., Science 316:1160-1166(2007).
Mohammed S., Anal. Chem. 81:4493-4501(2009)

References:

appl_detail:

Western blotting: 1:500~1:3000

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