Product Datasheet
APPL1 Antibody
Catalog Number: 34641
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q9UKG1
NCBI Gene ID: 26060
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human APPL1.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Adaptor protein APPL; Adaptor protein containing pH domain; PTB domain and leucine zipper motif; DIP13 alpha; DP13A
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total APPL1 protein.
- Background:
- Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.
Chen Y.Q., J. Biol. Chem. 277:26281-26285(2002).
Elledge S.J., Science 316:1160-1166(2007).
Mohammed S., Anal. Chem. 81:4493-4501(2009)
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