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NCAPH Antibody

Catalog Number:

34615
other_names: Condensin complex subunit 2; Non-SMC condensin I complex subunit H; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q15003
NCBI Gene ID: 23397

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human NCAPH.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NCAPH protein.

Applications:

WB

Background:

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Nomura N., DNA Res. 1:223-229(1994).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Cabello O.A., Mol. Biol. Cell 12:3527-3537(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

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