Product Datasheet
NCAPH Antibody
Catalog Number: 34615
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q15003
NCBI Gene ID: 23397
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human NCAPH.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Condensin complex subunit 2; Non-SMC condensin I complex subunit H; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total NCAPH protein.
- Background:
- Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Nomura N., DNA Res. 1:223-229(1994).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Cabello O.A., Mol. Biol. Cell 12:3527-3537(2001).
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