CD55 Antibody

Catalog Number:

34613

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P08174
NCBI Gene ID: 1604

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CD55.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CD55 protein.

Applications:

WB

Background:

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Caras I.W., Nature 325:545-549(1987).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ewulonu U.K., Proc. Natl. Acad. Sci. U.S.A. 88:4675-4679(1991).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF