Product Datasheet  
CD55 Antibody  
Catalog Number: 34613  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P08174
    NCBI Gene ID: 1604
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CD55.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • complement decay-accelerating factor; Cromer blood group; DAF; DAF1; decay accelerating factor for complement
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CD55 protein.
  • Applications：  
  • WB
  • Background：  
  • This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

    Caras I.W., Nature 325:545-549(1987).
    Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
    Ewulonu U.K., Proc. Natl. Acad. Sci. U.S.A. 88:4675-4679(1991).



 
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