CNGA1 Antibody

Catalog Number:

34577

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P29973
NCBI Gene ID: 1259

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CNGA1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CNGA1 protein.

Applications:

WB

Background:

Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.

Pittler S.J., J. Biol. Chem. 267:6257-6262(1992).
Dhallan R.S., J. Neurosci. 12:3248-3256(1992).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF