Product Datasheet  
CNGA1 Antibody  
Catalog Number: 34577  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P29973
    NCBI Gene ID: 1259
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CNGA1.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • cGMP-gated cation channel alpha 1; CNCG; CNCG1; CNG channel alpha 1; CNG-1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CNGA1 protein.
  • Applications：  
  • WB
  • Background：  
  • Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.

    Pittler S.J., J. Biol. Chem. 267:6257-6262(1992).
    Dhallan R.S., J. Neurosci. 12:3248-3256(1992).
    Ota T., Nat. Genet. 36:40-45(2004).



 
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