CEP152 Antibody

Catalog Number:

34565

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O94986
NCBI Gene ID: 22995

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CEP152.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEP152 protein.

Applications:

IHC

Background:

Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.

Nagase T., DNA Res. 5:355-364(1998).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Andersen J.S., Nature 426:570-574(2003).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF