Product Datasheet  
CEP152 Antibody  
Catalog Number: 34565  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O94986
    NCBI Gene ID: 22995
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human CEP152.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100
  • other_names：  
  • centrosomal protein 152 kDa; centrosomal protein 152kDa; centrosomal protein of 152 kDa;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total CEP152 protein.
  • Applications：  
  • IHC
  • Background：  
  • Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.

    Nagase T., DNA Res. 5:355-364(1998).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).
    Andersen J.S., Nature 426:570-574(2003).



 
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