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BCAS2 Antibody

Catalog Number:

34508
other_names: Pre-mRNA-splicing factor SPF27; Spliceosome-associated protein SPF 27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; BCAS2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: O75934
NCBI Gene ID: 10286

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human BCAS2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BCAS2 protein.

Applications:

WB

Background:

Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.

Neubauer G., Nat. Genet. 20:46-50(1998).
Nagasaki K., Cancer Lett. 140:219-226(1999).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

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