Product Datasheet
BCAS2 Antibody
Catalog Number: 34508
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: O75934
NCBI Gene ID: 10286
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human BCAS2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Pre-mRNA-splicing factor SPF27; Spliceosome-associated protein SPF 27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; BCAS2
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total BCAS2 protein.
- Background:
- Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.
Neubauer G., Nat. Genet. 20:46-50(1998).
Nagasaki K., Cancer Lett. 140:219-226(1999).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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