GLB1 Antibody

Catalog Number:

34494

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P16278
NCBI Gene ID: 2720

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human GLB1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GLB1 protein.

Applications:

WB

Background:

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. soform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.

Oshima A., Biochem. Biophys. Res. Commun. 157:238-244(1988) [PubMed: 3143362].
Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208].
Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707].

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF