Product Datasheet  
GLB1 Antibody  
Catalog Number: 34494  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P16278
    NCBI Gene ID: 2720
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human GLB1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Beta-galactosidase; EC=3.2.1.23; Acid beta-galactosidase; Lactase; Elastin receptor 1
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total GLB1 protein.
  • Applications：  
  • WB
  • Background：  
  • Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. soform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.

    Oshima A., Biochem. Biophys. Res. Commun. 157:238-244(1988) [PubMed: 3143362].
    Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208].
    Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707].




 
© Signalway Biotechnology All Rights Reserved.