ARG2 Antibody

Catalog Number:

34438

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P78540
NCBI Gene ID: 384

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human ARG2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARG2 protein.

Applications:

WB

Background:

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Gotoh T., FEBS Lett. 395:119-122(1996).
Vockley J.G., Genomics 38:118-123(1996).
Morris S.M. Jr., Gene 193:157-161(1997)

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF