Product Datasheet
ARG2 Antibody
Catalog Number: 34438
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P78540
NCBI Gene ID: 384
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human ARG2.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- Arginase-2 mitochondrial; Arginase II; Non-hepatic arginase; Kidney-type arginase;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ARG2 protein.
- Background:
- May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Gotoh T., FEBS Lett. 395:119-122(1996).
Vockley J.G., Genomics 38:118-123(1996).
Morris S.M. Jr., Gene 193:157-161(1997)
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