ADAMTS18 Antibody

Catalog Number:

34387

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8TE60
NCBI Gene ID: 170692

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ADAMTS18.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADAMTS18 protein.

Applications:

WB

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Cal S., Gene 283:49-62(2002) [PubMed: 11867212].
Martin J., Nature 432:988-994(2004) [PubMed: 15616553].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF