Product Datasheet
ADAMTS18 Antibody
Catalog Number: 34387
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q8TE60
NCBI Gene ID: 170692
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from internal of human ADAMTS18.
- appl_detail:
- Western blotting: 1:500~1:3000
- other_names:
- A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18EC=3.4.24.-;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total ADAMTS18 protein.
- Background:
- This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Cal S., Gene 283:49-62(2002) [PubMed: 11867212].
Martin J., Nature 432:988-994(2004) [PubMed: 15616553].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
© Signalway Biotechnology All Rights Reserved.