ACTR3 Antibody

Catalog Number:

34376

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P61158
NCBI Gene ID: 10096

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human ACTR3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACTR3 protein.

Applications:

WB

Background:

Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.

Welch M.D., J. Cell Biol. 138:375-384(1997).
Welch M.D., Nature 385:265-269(1997).
Gournier H., Mol. Cell 8:1041-1052(2001)

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF