Product Datasheet  
ACTR3 Antibody  
Catalog Number: 34376  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P61158
    NCBI Gene ID: 10096
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from C-terminal of human ACTR3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Actin-2; Actin-like protein 3; Actin-related protein 3; ACTR3;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ACTR3 protein.
  • Applications：  
  • WB
  • Background：  
  • Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.

    Welch M.D., J. Cell Biol. 138:375-384(1997).
    Welch M.D., Nature 385:265-269(1997).
    Gournier H., Mol. Cell 8:1041-1052(2001)



 
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