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ATN1 Antibody

Catalog Number:

34473
other_names: ATN1; Atrophin-1; Dentatorubral-pallidoluysian atrophy protein; DRPL;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P54259
NCBI Gene ID: 1822

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human ATN1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATN1 protein.

Applications:

WB

Background:

Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation By similarity. Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.

Nagafuchi S., Nat. Genet. 8:177-182(1994).
Onodera O., Am. J. Hum. Genet. 57:1050-1060(1995).
Margolis R.L., Brain Res. Mol. Brain Res. 36:219-226(1996).

References:

appl_detail:

Western blotting: 1:500~1:3000

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